Updated on 2021/05/27

写真a

 
Kazuya Furusawa
 

Research Interests

  • Polymer physics

  • Rheology

  • Food hydrogels

  • Biomaterial science

  • Tissue engineering

Research Areas

  • Life Science / Biomaterials

  • Life Science / Biomedical engineering

Education

  • Gunma University   Doctor's Course   Completed

    2003.4 - 2005.3

  • Gunma University   Doctor's Course   Completed

    2005.4 - 2008.3

Research History

  • Hokkaido University   Assistant Professor

    2008.8 - 2018.3

  • Kwansei Gakuin University   Researcher

    2008.4 - 2008.7

  • Fukui University of Technology   Associate Professor

    2018.4

 

Papers

  • Research report on the effective use of "Gibier" at 2019 in Japan Reviewed

    Memoirs of Fukui University of Technology   50   333 - 341   2020.10

  • Reports of activities for supporting starry sky sightseeing projects by "Food in Fukui" Reviewed

    Memoirs of Fukui University of Technology   50   347 - 352   2020.10

  • Osmotic gradients induce stable dome morphogenesis on extracellular matrix Reviewed

    Sumire Ishida-Ishihara, Masakazu Akiyama, Kazuya Furusawa, Isao Naguro, Hiroki Ryuno, Takamichi Sushida, Seiichiro Ishihara, Hisashi Haga

    Journal of Cell Science   133 ( 14 )   2020.7

  • Effects of Mechanical Properties and Morphologies of Collagen Hydrogels on Tissue Hierarchical Structures of 3D Engineered Muscle Tissues Reviewed

    Kazuya Furusawa

    2019 International Symposium on Micro-NanoMechatronics and Human Science   69 - 71   2019.12

     More details

    We have investigated an effect of elastic modulus on morphology of engineered muscle tissues. The engineered muscle tissues were constructed by culturing C2C12 cells in collagen hydrogels with multichannel structures (Multi-Channel Collagen Gels: MCCGs). To test the effect of elastic modulus of MCCGs on the tissue morphology, we modified the elastic modulus of MCCG by crosslinking with genipin. By comparing cellular morphology of C2C12 cells in MCCGs, we have shown that MCCG with genipin crosslinking supports cell adhesion and anisotropic elongation of C2C12 cells seeded in MCCG. The results suggests that a mechanical modification of MCCG is required for effectively culturing myoblasts and constructing functional engineered muscle tissues by using MCCG.

  • Anisotropic Multi-channel Collagen Gel (MCCG) Guides the Growth Direction of the Neurite-like Processes of PC12 Cells Reviewed

    Isabel Koh, Kazuya Furusawa & Hisashi Haga

    Scientific Reports   8   13901   2018.9

  • Effects of three-dimensional culture of mouse calvaria-derived osteoblastic cells in a collagen gel with a multichannel structure on the morphogenesis behaviors of engineered bone tissues Reviewed

    Saki Yahata, Kazuya Furusawa, Kei Nagao, Masahiro Nakajima, Toshio Fukuda

    ACS Biomaterials Science & Engineering   3   3414 - 3424   2017.12

  • Anisotropic Growth of Hydroxyapatite in Stretched Double Network Hydrogel Reviewed

    Kazuki Fukao, Takayuki Nonoyama, Ryuji Kiyama, Kazuya Furusawa, Takayuki Kurokawa, Tasuku Nakajima, Jian Ping Gong

    ACS Nano   11   12103 - 12110   2017.12

  • Small-angle X-ray and light scattering analysis of multi-layered Curdlan gels prepared by a diffusion method Reviewed

    Yasuyuki Maki, Kazuya Furusawa, Toshiaki Dobashi, Yasunobu Sugimoto, Katsuzo Wakabayashi

    Carbohydrate Polymers   155   136 - 145   2017.1

  • Determination of the elastic modulus of ?-lactoglobulin amyloid fibrils by measuring the Debye-Waller factor Reviewed

    Naoki Sasaki, Yuna Saitoh, Rajesh K. Sharma, Kazuya Furusawa

    International Journal of Biological Macromolecules   92   240 - 245   2016.11

  • Heterogeneous filament network formation by myosin light chain isoforms effects on contractile energy output of single cardiomyocytes derived from human induced pluripotent stem cells Reviewed

    Takeomi Mizutani, Kazuya Furusawa, Hisahi Haga, Kazushige Kawabata

    Regenerative Therapy   3   90 - 96   2016.3

  • Development of the evaluation system for barrier functions of engineered epithelial lumens Reviewed

    Kazuya Furusawa, Takeomi Mizutani, Naoki Sasaki

    Regenerative Therapy   3   82 - 89   2016.3

  • Morphology and properties of globular polymeric materials in the solid state: A composite material of DNA with a cationic surfactant Reviewed

    Emmanuel. C. Ossai, Yuka Tomimori, Shota Ohki, Koki Okada, Takeshi Yonekura, Kazuya Furusawa, Naoki Sasaki

    Journal of Polymer Science Part B: Polymer Physics   54   730 - 738   2015.12

  • Three-dimensional morphogenesis of MDCK cells induced by cellular contractile forces on a viscous substrate Reviewed

    Misako Imai, Kazuya Furusawa, Takeomi Mizutani, Kazushige Kawabata, Hisashi Haga

    Scientific Reports   5   14208   2015.9

  • Application of multichannel collagen gels in construction of epithelial lumen-like engineered tissues Reviewed

    Kazuya Furusawa, Takeomi Mizutani, Hiromi Machino, Saki Yahata, Akimasa Fukui, Naoki Sasaki

    ACS Biomaterials Science & Engineering   1   539 - 548   2015.5

  • Effect of a flow field on amyloid fibrillogenesis in a beta-lactoglobulin solution Reviewed

    Rajesh K. Sharma, Kazuya Furusawa, Akimasa Fukui, Naoki Sasaki

    International Journal of Biological Macromelecules   70   490 - 497   2014.7

  • Universality and specificity in molecular orientation in anisotropic gels prepared by diffusion method Reviewed

    Yasuyuki Maki, Kazuya Furusawa, Sho Yasuraoka, Hideki Okamura, Natsuki Hosoya, Mari Sunaga, Toshiaki Dobashi, Yasunobu Sugimoto, Katsuzo Wakabayashi

    Carbohydrate Polymers   108   118 - 126   2014.3

  • Elasitic properties of collagen in bone determined by measuring the Debye-Waller factor Reviewed

    Naoki Sasaki, Hideki Shirakawa, Tsutomu Nozoe, Kazuya Furusawa

    Journal of Biomechanics   46   2824 - 2830   2013.11

  • Multiscale analysis of changes in an anisotropic collagen gel structure by culturing osteoblasts Reviewed

    Yohei Hanazaki, Shoichi Sato, Jyun-ichi Masumoto, Kazuya Furusawa, Akimasa Fukui, Naoki Sasaki

    ACS Applied Materials & Interfaces   5   5937 - 5945   2013.6

  • Expression of xSDF-1?, xCXCR4, and xCXCR7 during gastrulation in Xenopus laevis Reviewed

    S. K. Mishra, Tomoko Nagata, Kazuya Furusawa, Naoki Sasaki, Akimasa Fukui

    International Journal of Developmental Biology   57   95 - 100   2013.3

  • Studies on the Formation Mechanism and the Structure of the Anisotropic Collagen Gel Prepared by Dialysis-Induced Anisotropic Gelation Reviewed

    Kazuya Furusawa, Shoichi Sato, Jyunichi Masumoto, Yohei Hanazaki, Yasuyuki Maki, Toshiaki Dobashi, Takao Yamamoto, Akimasa Fukui, Naoki Sasaki

    Biomacromolecules   13   29 - 39   2011.11

  • Change in the viscoelastic properties of agarose gel by HAp precipitation by osteoblasts cultured in an agarose gel matrix Reviewed

    Yohei Hanazaki, Daisuke Ito, Kazuya Furusawa, Akimasa Fukui, Naoki Sasaki

    Journal of Biorheology   26   21 - 28   2011.11

  • Wide Angle X-ray Diffraction and Small Angle X-ray scattering Studies on the Effect of Demineralization on Hierarchical Structure of Bone Reviewed

    Kazuya Furusawa, Hideki Shirakawa, Shoichi Sato, Yuka Tomimori, Bijei Giri, Akimasa Fukui, Naoki Sasaki

    Transactions of the Materials Research Society of Japan   36   387 - 391   2011.6

  • Anisotropic Structure of Calcium-Induced Alginate Gels by Optical and Small-Angle X-ray Scattering Measurements Reviewed

    Yasuyuki Maki, Kei Ito, Natsuki Hosoya, Chikayoshi Yoneyama, Kazuya Furusawa, Takao Yamamoto, Toshiaki Dobashi, Yasunobu Sugimoto, Katsuzo Wakabayashi

    Biomacromolecules   12   2145 - 2152   2011.4

  • Effect of pH on anisotropic gelation of DNA induced by aluminum cations Reviewed

    Kazuya Furusawa, Yoko Narazaki, Naoko Tomita, Toshiaki Dobashi, Naoki Sasaki, Takao Yamamoto

    The Journal of Physical Chemistry B   114   13923 - 13932   2010.10

  • Phase relationship and dynamics of anisotropic gelation of carboxymethylcellulose aqueous solution Reviewed

    S. C. Lin, Yoshiyuki Minamisawa, Kazuya Furusawa, Yasuyuki Maki, Hiroyuki Takeno, Takao Yamamoto, Toshiaki Dobashi

    Colloid and Polymer Science   288   695 - 701   2010.2

  • Aluminium Ion-Induced Anisotropic Gelation of DNA Reviewed

    Kazuya Furusawa, Yoshiyuki Minamisawa, Takao Yamamoto, Toshiaki Dobashi

    Soft Materials   7   132 - 149   2009.9

  • Optical Anisotropy of Calcium-Induced Alginate Gels Reviewed

    Yasuyuki Maki, Masako Wakamatsu, Kei Ito, Kazuya Furusawa, Takao Yamamoto, Toshiaki Dobashi

    Journal of Biorheology   23   24 - 28   2009.5

  • Carcinogen adsorbent prepared from DNA complex by gamma-ray irradiation Reviewed

    Kazuya Furusawa, Erika Kita, Toshiaki Saheki, Naotsugu Nagasawa, Norio Nishi, Toshiaki Dobashi

    Journal of Biomaterial Science: Polymer Edition   19   1159 - 1170   2008.9

  • Liquid crystalline gelation of aqueous solutions of structure proteins Reviewed

    Kazuya Furusawa, Hiroyuki Saito, Ai Tsugueda, Yoko Narazaki, Takao Yamamoto, Toshiaki Dobashi

    Transactions of the Materials Research Society of Japan   33   467 - 469   2008

  • Dynamics of DNA Liquid Crystalline Gelation Reviewed

    Kazuya Furusawa, Yoshiyuki Minamisawa, Toshiaki Dobashi, Takao Yamamoto

    The Journal of Physical Chemistry B   111   14423 - 14430   2007.11

  • Adsorption Kinetics of Carcinogens to DNA Liquid Crystalline Gel Beads Reviewed

    Kazuya Furusawa, Masako Wakamatsu, Toshiaki Dobashi, Takao Yamamoto

    Langmuir   23   10081 - 10087   2007.8

  • Carcinogenic Agents to DNA Gel Beads Reviewed

    Yasuyuki Maki, Kazuya Furusawa, Masako Wakamatsu, Takao Yamamoto, Toshiaki Dobashi

    Transactions of the Materials Research Society of Japan   32   799 - 802   2007

  • DNA liquid crystalline gel as adsorbent of carcinogenic agent Reviewed

    Toshiaki Dobashi, Kazuya Furusawa, Erika Kita, Yoshiyuki Minamisawa, Takao Yamamoto

    Langmuir   23   1303 - 1306   2006.12

  • Water and chain dynamics in polymer network structure Reviewed

    Yuya Umino, Satoshi Morishita, Rio Kita, Naoki Shinyashiki, Shin Yagihara, Kazuya Furusawa, Toshiaki Dobashi, Naotsugu Nagasawa

    Transactions of the Materials Research Society of Japan   31   767 - 770   2006

  • Mono- and Multilayered Aluminum ion-induced liquid crystalline gel of DNA Reviewed

    Yoshiyuki Minamisawa, Kazuya Furusawa, Takao Yamamoto, Toshiaki Dobashi

    Transactions of the Materials Research Society of Japan   31   739 - 741   2006

  • Structural and kinetic modification of aqueous hydroxypropylmethylcellulose (HPMC) induced by electron beam irradiation Reviewed

    Kazuya Furusawa, Toshiaki Dobashi, Satoshi Morishita, Mikio Oyama, Tadashi Hashimoto, Naoki Shinyashiki, Shin Yagihara, Naotsugu Nagasawa

    Physica A   353   9 - 20   2005.2

  • Nanometer-sized gelatin particles prepared by means of gamma-ray irradiation Reviewed

    Kazuya Furusawa, Ken Terao, Naotsugu Nagasawa, Fumio Yoshii, Kenji Kubota, Toshiaki Dobashi

    Colloid and Polymer Science   283   229 - 233   2004.10

  • Reagent free crosslinking of aqueous gelatin: manufacture and characteristics of gelatin gels irradiated with gamma ray and electron beam Reviewed

    Ken Terao, Naotsugu Nagasawa, Hirokazu Nishida, Kazuya Furusawa, Yasutaka Mori, Fumio Yoshii, Toshiaki Dobashi

    Journal Biomaterial Science Polymer Edition   14   1197 - 1208   2003.11

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Books

  • Nano/Micro Science and Technology in Biorheology: Principles, Methods, and Application

    Kazuya Furusawa( Role: Joint author ,  Chapter 12: Control of the multiscale structure of scaffolds and its application in tissue engineering)

    Springer  2015.6  ( ISBN:978-4-431-54886-7

MISC

  • Structure formation in biopolymer gels induced by diffusion of gelling factors

    Yasuyuki Maki, Kazuya Furusawa, Takao Yamamoto, Toshiaki Dobashi

    Journal of BIorheology   32 ( 2 )   27 - 38   2018.12

Presentations

  • 多管構造を持つコラーゲンゲルを用いた再生腸上皮組織の構築 International conference

    古澤和也

    第30回 日本MRS年次大会  日本MRS

     More details

    多管構造を持つコラーゲンゲルを使って腸陰窩構造を再現した再生腸上皮組織を作る方法について発表した。

  • Effects of Mechanical Properties and Morphologies of Collagen Hydrogels on Tissue Hierarchical Structures of 3D Engineered Muscle Tissues International conference

    Kazuya Furusawa

    2019 International Symposium on Micro-NanoMechatronics and Human Science  IEEE

     More details

    自律して運動するバイオロボットの駆動部品となる再生筋組織の階層構造に足場となるコラーゲンゲルの力学的性質と階層構造が与える影響を発表した。二つの再生筋組織の構築技術を開発した。一つは、多管構造を持つコラーゲンゲルを鋳型として用いる方法であり、もう一つはヌードル状の再生筋組織を構築する技術である。研究により、筋芽細胞の接着に適した弾性率があることと、足場の形態が構築される再生筋組織の組織形態を決定することを明らかにした。

  • コラーゲン水溶液の相挙動に関する研究

    杉山晃一, 古澤和也

    第41回日本バイオレオロジー学会年会  日本バイオレオロジー学会

 

Teaching Experience

  • Microbiology

    Institution:Fukui University of Technology

  • Physical Chemistry III

    Institution:Fukui University of Technology

  • Engineering English Exercise III

    Institution:Fukui University of Technology

  • Polymer Chemistry

    Institution:Fukui University of Technology